Subjects: Twelve volunteers with perennialallergicrhinitis.
2
Perennialallergicrhinitis with seasonal exacerbations is the most severe phenotype and most likely to be associated with difficult-to-control asthma.
1
And the turning point when the increase in the prevalence of wheezing, atopic dermatitis, and non-seasonalallergicrhinitis turned to decrease or constant was 1993.